Example of simulated parasite dynamics following treatment with a single dose of ART and 0 day treatment delay. A) Within-host parasite density over the first 50 days of infection and corresponding non-specific immune response (black bar). The coloured horizontal bars indicate three distinct phases post-treatment: dormancy (red), recovery (yellow) and renewed growth (green). B) Presence/absence of PfEMP1 variants that have > 10,000 parasites expressing the variant. Black: PfEMP1 variants where the corresponding anti-PfEMP1 antibodies were triggered prior to treatment. Green: PfEMP1 variants where corresponding anti-PfEMP1 antibodies were not triggered prior to treatment (ie density for parasites expressing variant prior to treatment did not reach the antibody threshold of 12 parasites/μl).