Table 4 Results of PCR on RDT and presence of antigen test lines for OptiMAL and SDFK60 tested with a panel of clinical samples
From: Rapid diagnostic tests as a source of DNA for Plasmodium species-specific real-time PCR
| Â | Â | Â | OptiMAL | SDFK60 | ||
|---|---|---|---|---|---|---|
| Â | Â | Â | Correct DNA detection by PCR on RDT | Correct antigen detection by RDT | Correct DNA detection by PCR on RDT | Correct antigen detection by RDT |
PCR on whole blood | Parasite density | Nrs | Nrs | Nrs | Nrs | Nrs |
P. falciparum | only gametocytes | 10 | 10 | 6 | 9 | 9 |
| Â | 1-100 | 10 | 10 | 4 | 10 | 10 |
| Â | 101-500 | 15 | 15 | 14 | 15 | 15 |
| Â | 501-1000 | 5 | 5 | 5 | 5 | 5 |
| Â | >1000 | 20 | 20 | 20 | 20 | 20 |
P. vivax | only gametocytes | 1 | 1 | 0 | 1 | 0 |
| Â | 1 to >1000 | 10 | 10 | 10 | 10 | 9 |
P. ovale | 1 to >1000 | 10 | 10 | 2 | 10 | 4 |
P. malariae | 1 to >1000 | 10 | 10 | 6 | 10 | 6 |
Total single infections | 0 to >1000 | 91 | 91 | 67 | 90 | 78 |
Mixed infections | 1 to >1000 | 5 | 4 | 3# | 2 | 1# |
After start of treatment | 0 | 15 | 11 | 1 | 7 | 15 |
Negative | 0 | 10 | 10 | 10 | 10 | 10 |
Total | Â | 121 | 116 | 81 | 109 | 104 |