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Figure 2 | Malaria Journal

Figure 2

From: Simple flow cytometric detection of haemozoin containing leukocytes and erythrocytes for research on diagnosis, immunology and drug sensitivity testing

Figure 2

Detection of Hz-containing monocytes and granulocytes in human whole blood. Top rows: Gating strategy for detection of haemozoin (Hz) containing monocytes (CD14+) and granulocytes (CD16+). Top row: blood from healthy donor without Hz, second row: incubated for 7 hours with synthetic haemozoin (0.06 μmol/ml heme-equivalent). Using plots from healthy volunteers (top row) gates were created to identify depolarizing monocytes and granulocytes. Bottom two rows: Colour backgating for samples shown in row one and two, as well as for a patient with P. falciparum malaria (0.2% parasitaemia). Blue = non-depolarizing monocytes, red = depolarizing monocytes, green = non-depolarizing granulocytes, orange = depolarizing granulocytes.

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Malaria Journal

ISSN: 1475-2875

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