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Table 6 Calculation of the RITAM score for Vernonia amygdalina leaf decoction

From: Do ethnobotanical and laboratory data predict clinical safety and efficacy of anti-malarial plants?

Component of Score Parameter Value Reference Score
Ethnobotanical Citation scores (see table1for details of calculation) [40] 0.5
[41] 0.6
[42] 0.9
[43] 0.6
[44] 0.6
[45] 0.5
[46] 0.5
[47] 0.8
Efficacy IC50in vitro 76.7 µg/ml [48] 0
% inhibition in vivo 62.7% [49] 6
Safety LD50 3320mg/kg [50] 6
TOTAL 17