n = 200 | |||||||||
---|---|---|---|---|---|---|---|---|---|
I 2002-2005 (n = 139) | II 2008-2010 (n = 61) | I | II | I | II | ||||
W | M | W | M | p | Combined genotypes | ||||
pfdhfr- 51 | 4.3 | 95.7 | 8.2 | 91.8 | 0.3 | pfdhfr -51I-59R-108N | Cuadruple pfdhf-pfdps | ||
pfdhfr- 59 | 5 | 95 | 8.2 | 91.8 | 0.5 | 51I-59R-108N-437G | |||
pfdhfr- 108 | 1.4 | 98.6 | 1.6 | 98.4 | 1 | 90.8 | 81.3 | 53.4 | 63.3 |
pfdhfr- 164 | 100 | 0 | 100 | 0 | 1 | Quintuple pfdhf-pfdps | |||
pfdhps- 436 | 87.7 | 12.3 | 100 | 0 | 0.004 | pfdhps -437G | 51I-59R-108N-437G-540E | ||
pfdhps- 437 | 29 | 71 | 16.4 | 83.6 | 0.05 | 18.4 | 16.3 | ||
pfdhps- 540 | 75.4 | 24.6 | 83.3 | 16.7 | 0.2 | 46.7 | 60 | 51I-59R-108N-437G-581G | |
pfdhps- 581 | 97.8 | 2.2 | 90 | 10 | 0.02 | 1 | 8.2 | ||
pfmdr1- 86 | 48.5 | 51.5 | 58.6 | 41.4 | 0.1 | ||||
pfmdr1- 1246 | 64.9 | 35.1 | 91.8 | 8.2 | 0.0001 | ||||
pfcrt- 76 | 4.4 | 95.6 | 3.4 | 96.6 | 1 |