Table 1 Summary of publications retrieved from MEDLINE and LILACS referring to clinical aspects of P. vivax malarial patients in Brazil (1948-2011)
| Â | Authors | Year of publication | Location City (State) | PCR confirmation | Age range (in years) | Number of patients | Type of clinical complication | Pregnancy | Death | Co-morbidity |
|---|---|---|---|---|---|---|---|---|---|---|
1 | Botelho et al. [25] | 1987 | Cuiabá (Mato Grosso) | No | NA | 41 | Pulmonary manifestations | No | No | NA |
2 | Moura et al. [26] | 1987 | NA | No | NA | 1 | Congenital malaria (?) | No | No | NA |
3 | Severo et al. [27] | 1994 | NA | No | NA | 112 | Hepatitis and jaundice | No | No | NA |
4 | Marques et al. [28] | 1996 | São Paulo (São Paulo) | No | 5 weeks | 1 | Congenital malaria and anaemia | No | No | NA |
5 | Siqueira-Batista et al. [29] | 1998 | Rio de Janeiro (Rio de Janeiro) | No | 62 | 1 | Cardiac arrhythmia after chloroquine use | No | No | NA |
6 | Ventura et al. [30] | 1999 | Belém (Pará) | No | 0-14 | 100 | Anaemia | No | No | Hookworms and malnutrition |
7 | Pinheiro et al. [31] | 2002 | Belém (Pará) | No | NA | 23 | Low birth weight | Yes | No | NA |
8 | Jarude et al. [32] | 2003 | Rio Branco (Acre) | No | 12-49 | 235 | Anaemia, jaundice, hepatitis and hypoglycaemia | Yes | No | NA |
9 | Lacerda et al. [33] | 2004 | Manaus (Amazonas) | Yes | 20 | 1 | ITP | No | No | No |
10 | Silva et al. [34] | 2004 | Belém (Pará) | No | 18-60 | 11 | Blackwater fever after primaquine use | No | No | G6PD deficiency |
11 | Melo et al. [35] | 2004 | Manaus (Amazonas) | No | 7-84 | 126 | Ocular lesions | No | No | Hypovitaminosis A |
12 | Braga et al. [36] | 2004 | Fortaleza (Ceará) | No | 25 | 1 | Neurological symptoms | No | No | NA |
13 | Lomar et al. [37] | 2005 | São Paulo (São Paulo) | No | 43 | 1 | ARDS | No | No | No |
14 | Vermehren et al. [38] | 2005 | Manaus (Amazonas) | No | 51 | 1 | Acute renal failure | No | No | No |
15 | Braga et al. [39] | 2006 | Coari (Amazonas) | No | 14-69 | 333 | Hepatitis | No | No | HBV |
16 | Cabral et al. [40] | 2006 | Manaus (Amazonas) | No | 4 | 1 | Blackwater fever, anaemia and ARDS | No | No | Sickle cell anaemia |
17 | Lacerda et al. [41] | 2007 | Manaus (Amazonas) | No | 23 | 1 | Splenic hematoma | No | No | NA |
18 | Santana et al. [42] | 2007 | Manaus (Amazonas) | No | 3-67 | 73 | Methaemoglobinemia after primaquine use | No | No | G6PD deficiency |
19 | Lacerda et al. [43] | 2008 | Maués (Amazonas) | Yes | 14 | 1 | Chronic splenomegaly and thrombocytopaenia | No | No | NA |
20 | Ramos Jr et al. [44] | 2010 | Manaus (Amazonas) | No | 8-39 | 18 | Blackwater fever after primaquine use | No | No | G6PD deficiency |
21 | Alexandre et al. [45] | 2010 | Manaus (Amazonas) | Yes | 0-80 | 17 | Jaundice, anaemia, shock, acute renal failure, ARDS and haemoglobinuria | No | Yes (1) | HAV, hypertension and diabetes |
22 | Siqueira et al. [46] | 2010 | Manaus (Amazonas) | Yes | 16 | 1 | Rhabdomyolysis | No | No | No |
23 | Melo et al. [47] | 2010 | Careiro (Amazonas) | No | 5-14 | 54 | Anaemia | No | No | Intestinal helminthes |
24 | Andrade et al. [48] | 2010 | Buritis (Rondônia) | Yes | 9-54 | 19 | Jaundice, anaemia, shock, acute renal failure and ARDS | No | Yes (6) | No |
25 | Chagas et al. [49] | 2010 | Manaus (Amazonas) | No | 9-44 | 411 | Vaginal bleeding and amniorrexis | Yes | No | NA |
26 | Fragoso et al. [50] | 2011 | Manaus (Amazonas) | Yes | 48 | 1 | Hypovolaemic shock after CQ use | No | No | Hemophilia A |
27 | Ferreira et al. [51] | 2011 | Macapá (Amapá) | No | 15-60 | 20 | Methaemoglobinemia after primaquine use | No | No | G6PD deficiency |