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Figure 4 | Malaria Journal

Figure 4

From: Evidence for in vitro and in vivo expression of the conserved VAR3 (type 3) plasmodium falciparum erythrocyte membrane protein 1

Figure 4

Immune serum reactivity to three IT/FCR3 Plasmodium falciparum parasite lines. The reactivity of 61 plasma samples from children living in malaria endemic Mgome, Tanzania, against three parasite lines expressing VAR3 (Group A PfEMP1), IT4var60 (Group A PfEMP1) and IT4var59 (Group B PfEMP1), respectively, was measured by flow cytometry and divided into age groups: [ 1- <3] n = 4; [3- <5] n = 6; [5- <10] n = 23; [10- <15] n = 19; [15- <19] n = 9. Danish controls n = 8. The PfEMP1 domain structures as previously described [23] are shown below each parasite seroprofile. Ends of whiskers in the boxplots represent the smallest and largest median of FITC fluorescence intensity (MFI) values in the given age group.

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Malaria Journal

ISSN: 1475-2875

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