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Table 1 Pearson’s correlation coefficient ( r) values (95% CI) for IC 50 comparisons of artemisinins

From: Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections

Drug

Artesunate

DHA

Artemether

Artemisinin

0.47 (0.11 – 0.72)

p = 0.012

0.42 (0.05 – 0.68)

p = 0.028

0.65 (0.37 – 0.82)

p = 0.0002

Artesunate

 

0.66 (0.39 – 0.83)

p = 0.0001

0.60 (0.29 – 0.79)

p = 0.0008

DHA

  

0.33 (−0.05 – 0.63)

p = 0.084