Table 2 Matched bivariate analysis between co-infected patients and pure malaria infected patients
Results n (%) | Co-infection (n = 104) | Malaria (n = 208) | p** |
|---|---|---|---|
Males | 75 (72.1) | 162 (77.9) | 0.26 |
Children (<15 years-old) | 11 (10.6) | 18 (8.7) | 0.58 |
Journey in forest | 26 (25) | 51 (24.6) | 0.96 |
Inhabitant of the coast ¥ | 86 (83.5) | 151 (74.4) | 0.11 |
Long admission (≥2 days) | 43 (41.3) | 72 (34.6) | 0.25 |
Admission | 37 (35.6) | 69 (33.2) | 0.67 |
Medical history of malaria | 52 (50) | 115 (62.8) | 0.02§ |
Time since last malaria attack < 90 days | 19 (55.9) | 49 (51.6) | 0.91 |
Medical history of dengue | 3 (3.4) | 16 (9) | 0.08§§ |
Duration of fever > 5 days | 48 (48.5) | 61 (29.9) | 0.001§ |
Red cells transfusion | 8 (7.7) | 3 (1.4) | 0.01§ |
Tachycardia (>90 bpm) | 79 (79) | 165 (82.1) | 0.64 |
Hypotension (<90 mmHg) | 10 (10.4) | 7 (3.6) | 0.01§ |
Fever ≥ 40°C | 15 (14.7) | 24 (11.9) | 0.47 |
Retro-orbital pain | 4 (3.9) | 10 (5) | 0.61 |
Chills | 36 (35.6) | 64 (32.2) | 0.7 |
Hemorrhagic signs | 12 (11.5) | 25 (12.4) | 0.81 |
Shock signs | 7 (6.8) | 8 (4) | 0.16§§ |
Rash | 1 (1) | 5 (2.5) | 0.4 |
Nausea and / or vomiting | 58 (56.9) | 93 (45.8) | 0.06§§ |
Neurological disorders | 7 (6.8) | 5 (2.5) | 0.08§§ |
Dehydration | 7 (7.4) | 10 (5) | 0.37 |
Mucocutaneous pallor | 11 (11.6) | 7 (3.5) | 0.02§ |
Splenomegaly | 9 (12.3) | 23 (18.3) | 0.08§ |
Mucocutaneous jaundice | 9 (8.7) | 9 (4.3) | 0.14§§ |
ENT symptoms | 6 (5.8) | 10 (4.8) | 0.72 |
Severe “malaria” cases†† | 34 (32,7) | 39 (18,7) | 0,007 |
Low parasitaemia (class < 3) | 20 (19.2) | 24 (11.5) | 0.08§§ |
Mildly low hemoglobin (<12 g/dl) | 37 (35.6) | 43 (20.7) | 0.05§§ |
Low hematocrit (<36%) | 43 (41.3) | 49 (23.6) | 0.002§ |
Deep thrombocytopenia (<50 G/L) | 23 (22.1) | 25 (12) | 0.02§ |
Low prothrombin (<70%) | 14 (21.2) | 22 (15.4) | 0.33 |
Hyponatremia (<130) | 7 (7.1) | 15 (7.4) | 0.87 |
Hypokalemia (<3) | 6 (6.1) | 15 (7.4) | 0.67 |
Elevated creatinin (>111 μmol/L) | 4 (4) | 14 (7) | 0.29 |
Elevated bilirubin (>50 μmol/L) | 16 (16.8) | 20 (10.5) | 0.06 |
SGPT (>2 N) | 10 (10.2) | 33 (16.7) | 0.16§ |
SGOT >2 N | 13 (13.3) | 23 (11.6) | 0.66 |
CRP <5 | 2 (2) | 1 (0.5) | 0.22 |
CRP 5 à 50 | 29 (29) | 78 (38) | - |
CRP > 50 | 69 (69) | 126 (61.5) | - |