Skip to main content

Table 3 Histological analysis by treatment arm

From: Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial

   Quinine AL p p-adjusted
Formalin pigment n (%) 8/97 (8.2%) 8/98 (8.2%) 0.983 0.984
Haemozoin present n (%) 60/89 (67.4%) 58/90 (64.4%) 0.675 0.954
Haemozoin (% of HPF) Median [IQR]; n 3.3 [0-10.6]; 88 1.5 [0-5.7]; 90 0.090 0.101
Haemozoin >10% of HPF n (%) 23/89 (25.8%) 12/90 (13.3%) 0.031 0.028
Inflammation n (%) 8/97 (8.2%) 8/98 (8.2%) 0.999 0.974
Parasitized RBC n (%) 5/89 (5.6%) 8/90 (8.9%) 0.566 0.241
  1. Adjusted p-values are corrected for day of enrolment, gravidity, parasitemia at enrolment and reinfection. AL- artemether-lumefantrine; HPF- high power fields.