Table 1 Characteristics of study subjects by the study drug on enrolment
Characteristic | Artemisinin- naphthoquine(AN) | Dihydroartemisinin- piperaquine(DHP) | P | Overall |
|---|---|---|---|---|
Number of subjects | 201 | 200 | Â | 401 |
Age:mean ± SD (range) years | 27.6 ± 10.8 (15–69) | 26.2 ± 9.2 (15–67) | 0.18 | 26.9 ± 10.0 (15–69) |
Body weight: mean ± SD (range) kgs | 58.7 ± 8.5 (36–81) | 58.5 ± 8.5 (37–85) | 0.86 | 58.6 ± 8.5 (36–85) |
Axillary temperature: mean ± SD (range) °C | 37.9 ± 1.0 (36–40.3) | 37.9 ± 1.1 (35–40.2) | 0.84 | 37.9 ± 1.1 (35–40.3) |
Blood Pressure Systole: mean ± SD (range) mmHg | 113 ± 13 (90–150) | 114 ± 13 (80–170) | 0.44 | 113 ± 13 (80–170) |
Diastole: mean ± SD (range) mmHg | 72 ± 9 (50–92) | 73 ± 9 (40–120) | 0.39 | 72 ± 9 (40–120) |
Heart rate: mean ± SD (range) per min | 86 ± 13 (52–126) | 87 ± 13 (56–126) | 0.59 | 86 ± 13 (52–126) |
Respiration rate: mean ± SD (range) per min | 20 ± 3 (16–36) | 20 ± 3 (16–32) | 0.51 | 20 ± 3.0 (16–36) |
Sex: male:female (%) | 181:20 (90:10) | 170:30 (85:15) | 0.17 | 351:50 (87.5:12.5) |
History of fever in the last 24 hours (%) | 195 (97.0) | 199 (99.5) | 0.12 | 394 (98.3) |
Study subject with T.axillary ≥37.5°C (%) | 114 (56.7) | 109 (54.5) | 0.73 | 223 (55.6) |
History of experience malaria in the last year (%) | 160 (79.6) | 159 (79.5) | 1.00 | 319 (79.6) |
Frequency of malaria in the last year: mean ± SD (range) times | 2.6 ± 2.3 (1–20) | 2.4 ± 1.6 (1–12) | 0.53 | 2.7 ± 3 (1–20) |
History of taken antimalarial drugs in the last 4 weeks (%) | 55 (27.4) | 57 (28.5) | 0.89 | 112 (27.9) |