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Table 1 Characteristics of study subjects by the study drug on enrolment

From: Efficacy and safety of artemisinin-naphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia

Characteristic Artemisinin- naphthoquine(AN) Dihydroartemisinin- piperaquine(DHP) P Overall
Number of subjects 201 200   401
Age:mean ± SD (range) years 27.6 ± 10.8 (15–69) 26.2 ± 9.2 (15–67) 0.18 26.9 ± 10.0 (15–69)
Body weight: mean ± SD (range) kgs 58.7 ± 8.5 (36–81) 58.5 ± 8.5 (37–85) 0.86 58.6 ± 8.5 (36–85)
Axillary temperature: mean ± SD (range) °C 37.9 ± 1.0 (36–40.3) 37.9 ± 1.1 (35–40.2) 0.84 37.9 ± 1.1 (35–40.3)
Blood Pressure Systole: mean ± SD (range) mmHg 113 ± 13 (90–150) 114 ± 13 (80–170) 0.44 113 ± 13 (80–170)
Diastole: mean ± SD (range) mmHg 72 ± 9 (50–92) 73 ± 9 (40–120) 0.39 72 ± 9 (40–120)
Heart rate: mean ± SD (range) per min 86 ± 13 (52–126) 87 ± 13 (56–126) 0.59 86 ± 13 (52–126)
Respiration rate: mean ± SD (range) per min 20 ± 3 (16–36) 20 ± 3 (16–32) 0.51 20 ± 3.0 (16–36)
Sex: male:female (%) 181:20 (90:10) 170:30 (85:15) 0.17 351:50 (87.5:12.5)
History of fever in the last 24 hours (%) 195 (97.0) 199 (99.5) 0.12 394 (98.3)
Study subject with T.axillary ≥37.5°C (%) 114 (56.7) 109 (54.5) 0.73 223 (55.6)
History of experience malaria in the last year (%) 160 (79.6) 159 (79.5) 1.00 319 (79.6)
Frequency of malaria in the last year: mean ± SD (range) times 2.6 ± 2.3 (1–20) 2.4 ± 1.6 (1–12) 0.53 2.7 ± 3 (1–20)
History of taken antimalarial drugs in the last 4 weeks (%) 55 (27.4) 57 (28.5) 0.89 112 (27.9)