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Table 2 Haematology, blood chemistry and parasitology findings of study subjects on enrolment by the study drug

From: Efficacy and safety of artemisinin-naphthoquine versus dihydroartemisinin-piperaquine in adult patients with uncomplicated malaria: a multi-centre study in Indonesia

Parameter Artemisinin- naphthoquine (AN) Dihydroartemisinin- piperaquine (DHP) P Overall
Number of subjects 201 200   401
Haematocrit: mean ± SD (range)% 36.1 ± 7.1 (15.5–68.9) 36.6 ± 6.6 (19.1–63.4) 0.46 36.4 ± 6.8 (15.5–68.9)
Haemoglobin: mean ± SD (range) g/dL 12.5 ± 2.3 (6.2–23.1) 12.6 ± 2.1 (6.6–21.1) 0.67 12.6 ± 2.2 (6.2–23.1)
Red Blood Cell: mean ± SD (range) per uL 4.5 ± 0.8 (1.5–7.7) 4.4 ± 0.8 (2.2–7.3) 0.70 4.4 ± 0.8 (1.5–7.7)
Platelet: mean ± SD (range) 10 3 /mm 3 116.4 ± 68.7 (1.8–381.0) 116.5 ± 65.9 (1 .0–601.0) 0.98 116 ± 67.2 (1.0–601.0)
White Blood Cell: mean ± SD (range) per uL 6.4 ± 2.2 (2.0–14.0) 7.1 ± 6.0 (2.2–65.0) 0.11 6.8 ± 4.5 (2.0–65.0)
Bilirubin: mean ± SD (range) mg/dL 1.0 ± 0.6 (0.1–5.2) 1.0 ± 0.5 (0.1–3.8) 0.67 1.0 ± 0.5 (0.1–5.2)
Albumin: mean ± SD (range) g/dL 4.1 ± 1.0 (2.0–7.4) 4.2 ± 1.0 (2.2–6.2) 0.25 4.2 ± 1.0 (2.1–7.4)
ALT (SGPT): mean ± SD (range) IU/L 28.8 ± 13.0 (5–73) 28.3 ± 14.2 (6.9–98.0) 0.71 28.5 ± 13.9 (5.0–98.0)
AST (SGOT): mean ± SD (range) IU/L 29.4 ± 14.0 (2.0–87.0) 28.5 ± 11.8 (2.6–91.0) 0.49 28.9 ± 12.9 (2.0–91.0)
Creatinine: mean ± SD (range) mg/dL 1.0 ± 0.4 (0.2–2.5) 0.9 ± 0.3 (0.2–2.0) 0.15 0.9 ± 0.4 (0.2–2.5)
Urea: mean ± SD (range) mg/dL 27.5 ± 11.7 (2.7–80.0) 27.6 ± 11.7 (8.6–110.0) 0.94 27.6 ± 11.7 (2.7–110.0)
Density of asexual parasites: geometric mean (range) per uL 6310 (304–113550) 6972 (372–140084) 0.21 6634 (304–140084)
Gametocyte carriages (%) 134 (67.3) 140 (70.3) 0.54 274 (68.8)
Density of gametocytes: geometric mean (range) per uL 40 (1–2697) 35 (2–2208) 0.55 38 (1–2697)