Table 3 The distribution of mutations in different clinical responses
CQ RESPONSE | Â | ASSAMa | ORISSA | JHARKHAND | W.BENGAL | GUJARAT | GOA | TAMIL NADU | RAJASTHAN | TOTAL |
|---|---|---|---|---|---|---|---|---|---|---|
ACPR | pfcrt haplotype b | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | CVMNK-A | 0 | 11(45.83) | 7(41.17) | 0 | 0 | 0 | 0 | 1(3.85) | 19(17.92) |
| Â | CVIET-S | 5(41.66) | 3(12.50) | 6(35.29) | 1(14.28) | 0 | 0 | 0 | 0 | 15(14.15) |
| Â | S VMNT-A | 0 | 1(4.16) | 0 | 0 | 0 | 0 | 0 | 0 | 1(0.94) |
| Â | S VMNT-S | 7(58.33) | 9(37.50) | 4(23.52) | 6(85.71) | 6(100) | 8(100) | 6(100) | 25(96.25) | 71(66.98) |
| Â | pfmdr mutation c | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | N86 wt | 1(9.09) | 18(75.00) | 13(76.47) | 6(85.71) | 6(100) | 8(100) | 6(100) | 21(80.76) | 79(75.23) |
| Â | N86Y mt | 10(90.90) | 6(25.00) | 4(23.52) | 1(14.28) | 0 | 0 | 0 | 5(19.23) | 26(24.76) |
| Â | Combined genotype b | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | CVMNKA N | 0 | 9(37.50) | 7(41.17) | 0 | 0 | 0 | 0 | 1(3.85) | 17(16.19) |
| Â | CVMNKA Y | 0 | 2(8.33) | 0 | 0 | 0 | 0 | 0 | 0 | 2(1.90) |
| Â | S VMNTS N | 0 | 6(25.00) | 1(5.88) | 6(85.71) | 6(100) | 8(100) | 6(100) | 20(76.92) | 53(50.47) |
| Â | S VMNTS Y | 6(54.54) | 3(12.50) | 3(17.64) | 0 | 0 | 0 | 0 | 5(19.23) | 17(16.19) |
| Â | S VMNT A N | 0 | 1(4.16) | 0 | 0 | 0 | 0 | 0 | 0 | 1(0.95) |
| Â | CVIETS N | 1(9.09) | 2(8.33) | 5(29.41) | 0 | 0 | 0 | 0 | 0 | 8(7.61) |
| Â | CVIETS Y | 4(36.36) | 1(4.16) | 1(5.88) | 1(14.28) | 0 | 0 | 0 | 0 | 7(6.66) |
ETF | pfcrt haplotype | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | CVIET-S | 2(40) | 4(66.66) | 2(100) | 1(50) | 0 | 1(11.11) | 0 | 0 | 10(40.00) |
| Â | S VMNT-S | 3(60) | 2(33.33) | 0 | 1(50) | 1(100) | 8(88.88) | 0 | 0 | 15(60.00) |
| Â | pfmdr mutation | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | N86 wt | 4(80) | 2(33.33) | 1(50) | 1(50) | 1(100) | 9(100) | 0 | 0 | 18(72.00) |
| Â | N86Y mt | 1(20) | 4(66.66) | 1(50) | 1(50) | 0 | 0 | 0 | 0 | 7(28.00) |
| Â | combined genotype | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | S VMNTS N | 2(40) | 1(16.66) | 0 | 1(50) | 1(100) | 8(88.88) | 0 | 0 | 13(52.00) |
| Â | S VMNTS Y | 1(20) | 1(16.66) | 0 | 0 | 0 | 0 | 0 | 0 | 2(8.00) |
| Â | CVIETS N | 2(40) | 1(16.66) | 1(50) | 0 | 0 | 1(11.11) | 0 | 0 | 5(20.00) |
| Â | CVIETS Y | 0 | 3(50.00) | 1(50) | 1(50) | 0 | 0 | 0 | 0 | 5(20.00) |
LTF | pfcrt haplotype | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | CVIET-S | 8(88.88) | 10(41.66) | 12(80) | 2(28.57) | 0 | 0 | 0 | 0 | 32(29.35) |
| Â | S VMNT-S | 1(11.11) | 14(58.33) | 2(13.33) | 5(71.42) | 26(100) | 9(100) | 19(100) | 0 | 76(69.72) |
| Â | CVMDT-S | 0 | 0 | 1(6.66) | 0 | 0 | 0 | 0 | 0 | 1(0.91) |
| Â | pfmdr mutation | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | N86 wt | 1(11.11) | 8(33.33) | 4(26.66) | 5(71.42) | 25(96.15) | 9(100) | 18(94.73) | 0 | 70(64.22) |
| Â | N86Y mt | 8(88.88) | 16(66.66) | 11(73.33) | 2(28.57) | 1(3.84) | 0 | 1(5.26) | 0 | 39(35.77) |
| Â | combined genotype | Â | Â | Â | Â | Â | Â | Â | Â | Â |
| Â | S VMNTS N | 1(11.11) | 3(12.50) | 0 | 5(71.42) | 25(96.15) | 9(100) | 18(94.73) | 0 | 61(55.96) |
| Â | S VMNTS Y | 0 | 11(45.83) | 2(13.33) | 0 | 1(3.84) | 0 | 1(5.26) | 0 | 15(13.76) |
| Â | CVIETS N | 0 | 5(20.83) | 5(33.33) | 0 | 0 | 0 | 0 | 0 | 10(9.17) |
| Â | CVIETS Y | 8(88.88) | 5(20.83) | 7(46.66) | 2(28.57) | 0 | 0 | 0 | 0 | 22(20.18) |
| Â | CVMDTS Y | 0 | 0 | 1(6.66) | 0 | 0 | 0 | 0 | 0 | 1(0.91) |