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Table 2 Incidence, relative risk and attributable risk of mild malaria among carriers of TLR9 SNP’s genotypes

From: Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study

aSNPs Incidence Relative risk Attributable risk bCI p value cpc
rs187084
(C-1486 T)
      
TT vs. CC + TC 0.04 0.37 −0.061 (−0.11)-(−0.01) 0.01 ns
CC vs. TT + TC 0.20 3.7 0.144 0.03-0.26 0.01 ns
rs5743836
(C-1237 T)
      
TT vs. CC + TC 0.04 0.38 −0.060 (−0.11)-(−0.01) 0.01 ns
CC vs. TT + TC 0.09 1.29 0.020 (−0.05)-(0.09) 0.6 ns
rs352139
(G + 1174A)
      
GG vs. AA + GA 0.15 4.8 0.116 0.05-0.18 0.0003 0.0024
AA vs. GG + GA 0.03 0.3 −0.055 (−0.10)-(−0.01) 0.03 ns
rs352140 (G + 2848A)       
GG vs. AA + GA 0.04 0.3 −0.076 (−0.13)-(−0.02) 0.006 0.048
AA vs. GG + GA 0.11 1.63 0.044 (−0.08)-(0.17) 0.5 ns
  1. aSNPs: Single nucleotide polymorphisms; bCl: confidence intervals; cpc = corrected p value by bonferroni method by factor of 8; ns: not statistically significant. The incidence shown is for the genotype highlighted in bold, the relative and attributable risk shown are for the same genotype when compared with the non-carriers of the genotype. Corrected p value <0.05 was considered to be statistically significant.