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Table 3 Incidence, relative risk and attributable risk of mild malaria among carriers of TLR9 haplotypes

From: Toll-like receptor 9 (TLR9) polymorphism associated with symptomatic malaria: a cohort study

aHaplotype Incidence Relative risk Attributable risk bCI p value c p c
TTAG vs. non-TTAG 0.03 0.2 −0.115 (−0.16)-(−0.07) 8x10 -7 4x10 -6
CTGA vs. non-CTGA 0.15 3.3 0.103 0.04-0.16 0.001 0.005
TCGG vs. non TCGG 0.10 1.5 0.032 (−0.03)-(0.09) 0.3 ns
CCGG vs. non-CCGG 0.12 2.1 0.063 0.0-0.1 0.05 ns
TCGA vs. non-TCGA 0.09 1.2 0.012 (−0.07)-(0.09) 0.8 ns
  1. aHaplotype for rs187084 (C-1486 T), rs5743836 (C-1237 T), rs352139 (G + 1174A) and rs352140 (G + 2848A), respectively; bCl: confidence intervals; cpc = corrected p value by Bonferroni’s method by a factor of 5; ns: not statistically significant. The incidence shown is for the haplotype highlighted in bold, the relative and attributable risk shown are for the same haplotype when compared with the non-carriers of the haplotype. Corrected p value <0.05 was considered to be statistically significant.