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Table 1 Inhibition of erythroid expansion by lysate of infected erythrocytes to CD34 + cells /erythroid progenitor cells

From: Suppression of erythroid development in vitro by Plasmodium vivax

Day-old of cell cultures

% of control (mean ± S.D.)

IE

IE

UE

UE

TNF-a

1

10

1

10

25 ng/ml

1

67 ± 9.5*

43 ± 5.5*

100 ± 4.5

98 ± 5.5

54 ± 12*

5

72 ± 6.5*

58 ± 4.5*

99 ± 4.0

98 ± 4.8

69 ± 8*

8

88 ± 4.5

65 ± 7.5*

99 ± 2.0

99 ± 5.5

74 ± 7*

11

98 ± 8.5

87 ± 7.0*

100 ± 4.5

100 ± 5.0

78 ± 6*

  1. * P-value < 0.01 compared with control wells.
  2. Inhibition is presented as percentage of expansion of the control after three day-culture without added medium, cells, or TNF-a. Lysates of infected erythrocyte (IE) and uninfected erythrocyte (UE) were added at ratios of 1 or 10 IE / UE per 1 CD34+ cells / erythroid progenitor cells. The mean and S.D. were calculated from five independent experiments.
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Malaria Journal

ISSN: 1475-2875

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