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Table 3 Efficacy outcome for ASAQ and AL on day 42, calculated by PP analysis and Kaplan-Meier analysis

From: Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial

  PP cure rate analysis Kaplan Meier cure rate analysis
ASAQ AL ASAQ AL
PCR unadjusted
n/N 13/131 19/125 12/156 18/145
% efficacy [CI95%] 90.1 [83.6-94.6] 84.8 [77.3-90.6] 90.9 [84.6-94.8] 85.8 [78.4-90.8]
% difference (LLCI*) −5.2 (−0.02)  
PCR adjusted
n/N 2/120 1/107 2/146 1/137
% efficacy [CI95%] 98.3 [94.1-99.8] 99.1 [94.9-99.9] 98.4 [93.8-99.6] 99.2 [94.3-99.9]
% difference (LLCI*) −0.7 (−3.1)  
  1. *LLCI : lower limit of the one-sided 90%CI.