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Figure 4 | Malaria Journal

Figure 4

From: Activation of nuclear factor kappa B in peripheral blood mononuclear cells from malaria patients

Figure 4

Malaria sera-induced NF-κB p65 activation in the PBMCs of healthy controls (n = 5). The protein extracts (10 μg/well) of the PBMCs from healthy controls after stimulation with serum from malaria patients were analysed for phospho-NF-κB level using ELISA. The results demonstrated significantly increased levels of phospho-NF-κB p65 in the PBMCs in response to malaria-patient sera after 30 min of stimulation with 10% serum from malaria patients with P. vivax, uncomplicated P. falciparum, and complicated P. falciparum malaria. TNF treatment was used as positive control and PBMCs treated with media was used as untreated or negative control. *Significance of p < 0.05 compared to normal serum treatments (Student t-test). ΔSignificance of p < 0.05 compared between groups. Data are presented as mean ± SEM.

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