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Figure 4 | Malaria Journal

Figure 4

From: Plasmodium serine hydroxymethyltransferase as a potential anti-malarial target: inhibition studies using improved methods for enzyme production and assay

Figure 4

MS analysis of compounds resulting from the reaction of PLP with thiosemicarbazide (A) and PvSHMT with thiosemicarbazide (B).

Compounds generated from these reactions are similar because they have the same parental mass (MW 318.9, indicated by arrow) and fragmentation pattern (MW 224.7, 242.7, 259.7 and 301.8, insets of A and B), which are in agreement to that of the PLP-thiosemicarbazone adduct. (C) Chemical structure of PLP-thiosemicarbazone.

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Malaria Journal

ISSN: 1475-2875

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