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Table 2 Clinical characteristics at the time of recrudescent and new infection compared to participants at the end of the study without recurrent infection

From: Clinical manifestations of new versus recrudescent malaria infections following anti-malarial drug treatment

 

Distribution

Odds ratio (95% CI) univariate

P value

Odds ratio (95% CI) Multivariate Recrudescent vs. new

P value

Proportion (%)

Fever

No

11/277(3.9)

Referent

   

Recrudescent

26/119 (21.8)

6.8 (3.2-14.3)

<.001

Referent

 

New

13/84 (15.4)

4.4 (1.9-10.3)

.001

.6 (.2-1.5)

.27

Anaemia

No

137/275 (49.8)

Referent

   

Recrudescent

81/117 (69.2)

2.3 (1.4-3.7)

.001

Referent

 

New

54/83 (65.1)

1.9 (1.1-3.2)

.017

1.5 (.7-3.2)

.34

 

Mean (95% CI)

   

Change in haemoglobin

No

.9 (.8-1.2)

   

Recrudescent

.7 (.4-1.0)

.2

Referent

 

New

1.2 (.7-1.6)

.4

1.3 (1.1-1.6)

.01

Multiplicity of infection

No

N/A

   

Recrudescent

2.7 (2.3-3.0)

 

Referent

 

New

2.3 (2.1-2.6)

.1

.8 (.6-1.0)

.05