Skip to main content

Advertisement

Table 3 Variation in geometric mean malaria parasitaemia density with age, gender, ethnicity and location across the major clinical subgroups

From: Severe and uncomplicated falciparum malaria in children from three regions and three ethnic groups in Cameroon: prospective study

Parameters N All subjects N CM n SMA n UM P value
Age group          
 < 60 642 10,451 40 8,940 177 10,089 120 6,791 0.415
 ≥ 60 159 5,998 8 6,978 27 2,037 68 8,954 0.046
P value   0.013   0.831   0.001   0.504  
Gender          
 Male 472 7,773 22 7,968 110 7,636 126 4,405 0.223
 Female 421 10,293 26 9,130 121 7,862 102 11,592 0.582
P value   0.087   0.876   0.835   0.007  
Ethnicity          
 Bantu 360 9,134 21 6,246 90 7,962 96 7,638 0.927
 Semi-Bantu 391 11,171 23 10,993 103 9,670 79 10,194 0.973
 Foulbe 30 9,387 2 4,205 5 1,336 5 13,402 0.522
P value   0.539   0.789   0.156   0.738  
Location          
 Centre 162 17,640 5 9,908 60 10,336 20 43,031§ 0.014
 Littoral 281 7,292 32 6,296 58 5,243 18 7,385 0.873
 South West 452 7,836 11 19,756 113 8,136 190 5,540 0.161
P value   0.001   0.547   0.258   0.005  
Transmission          
 Seasonal 162 17,640 5 9,908 60 10,336 20 43,031§ 0.014
 Perennial 733 7,623 43 8,435 171 7,010 208 5,686 0.555
P value   <0.001   0.910   0.296   0.001  
  1. Each participant has been categorised into one group only which clinicians felt was the primary phenotype; Significantly higher than the corresponding values for SMA (P = 0.035).
  2. §Significantly higher than the corresponding values for SMA (P = 0.006) and patients from the South West region (P = 0.004).
  3. Significantly higher than the corresponding values for the Littoral (P = 0.001) and South West regions (P = 0.002).
  4. Each participant has been categorised into one group only which clinicians felt was the primary phenotype; Samples numbers in some of the clinical groups are lower because some parameter estimates were not taken.