Table 4 Univariate and multivariate analysis of obstetric outcome
From: Pharmacovigilance of artemether-lumefantrine in pregnant women followed until delivery in Rwanda
Frequency | Univariate analysis | Multivariate analysis | ||||||
|---|---|---|---|---|---|---|---|---|
Total no. of patients | No. of patients With adverse events with obstetric complications (total = 127) | OR | 95% CI | P- Value | OR | 95% CI | P-Value | |
Group | ||||||||
Pregnant women & malaria & AL treatment | 1030 | 78(7.3%) | 1.48 | 1.03, 2.15 | 0.36 | 1.38 | 0.95, 2.01 | 0.09 |
Healthy pregnant women | 937 | 49 (5.0%) | ||||||
Trimester | ||||||||
First trimester | 137 | 10 (7.3%) | 1.15 | 0.59, 2.25 | 0.74 | 1.04 | 0.53, 2.05 | 0.913 |
2 &3rd trimester | 1830 | 117(6.4%) | ||||||
Gravidity | ||||||||
Primigravidae | 529 | 53(10.0%) | 2.05 | 1.42, 2.97 | <0.001 | 2.65 | 1.71, 4.12 | <0.001 |
Multigravidae | 1438 | 74(5.1%) | ||||||
Mothers age (covariate) | 1.048 | 1.01, 1.09 | 0.009 | |||||