Figure 6

Phylogenetic comparison of 3 dominant DBLα sequence tags transcribed from each clinical isolates and selected tags from 3D7. A neighbor-joining tree was generated using amplified DBL-1α fragments. The bootstrap consensus tree inferred from 1000 replicates [45], using pairwise deletion of amino acid sequences with p-distance. Phylogenetic analyses were conducted in MEGA4 [39]. Sequences transcribed by isolates from children with severe malaria (ISM, pink), asymptomatic malaria (IAM,black) and 3D7 genes (group A, red; group B, blue; group C, green).