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Table 1 Baseline Characteristics by site and overall

From: Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India

  Guwahati Goa Mangalore TOTAL
DP A+M DP A+M DP A+M DP A+M
(N=46) (N=22) (N=19) (N=9) (N=36) (N=18) (N=101) (N=49)
Gender (n)
Male : female   17: 5 19: 0 8 : 1 32 : 4 17 : 1 78 : 23 42 : 7
Age (years)
Mean 29.1 31.2 25.9 26.1 28.5 27.7 28.3 29.0
SD 10.9 10.2 5.5 6.8 9.6 7.8 9.6 8.9
Weight (kg)
Mean 46.7 48.6 54.3 51.0 52.9 50.2 50.4 49.6
SD 7.8 7.9 8.8 3.3 6.6 5.5 8.2 6.4
Race (Asian)
% 100 100 100 100 100 100 100 100
Presence of fever
N 46 22 17 9 36 18 99 49
% 100 100 89 100 100 100 100 100
Temperature (°C)
Mean 37.9 37.9 38.9 38.6 38.9 38.8 38.4 38.4
SD 0.32 0.28 0.92 0.48 0.41 0.48 0.67 0.57
Parasitaemia (μ/L)
Geometric mean 5337.7 5915.1 7547.7 6650.2 6265.1 3279.3 6032.0 4866.3
Hb (g/L)
Mean 98.4 91.1 124.2 113.7 105.7 116.2 105.8 105
SD 25.1 21.0 22.5 19.3 21.9 23.5 25.1 24.5
Populations
Safety/ITT N 46 22 19 9 36 18 101 49
% 100 100 100 100 100 100 100 100
Per Protocol N 42 22 19 8 19 11 80 41
  % 91 100 100 89 53 61 79 84
  1. DP = dihydroartemisinin-piperaquine; A + M = artesunate-mefloquine; SD = standard deviation; fever was considered present if temperature was greater or equal to 37.5 °C; Hb = Haemoglobin.