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Table 1 Baseline Characteristics by site and overall

From: Therapeutic efficacy and safety of dihydroartemisinin-piperaquine versus artesunate-mefloquine in uncomplicated Plasmodium falciparum malaria in India

 

Guwahati

Goa

Mangalore

TOTAL

DP

A+M

DP

A+M

DP

A+M

DP

A+M

(N=46)

(N=22)

(N=19)

(N=9)

(N=36)

(N=18)

(N=101)

(N=49)

Gender (n)

Male : female

 

17: 5

19: 0

8 : 1

32 : 4

17 : 1

78 : 23

42 : 7

Age (years)

Mean

29.1

31.2

25.9

26.1

28.5

27.7

28.3

29.0

SD

10.9

10.2

5.5

6.8

9.6

7.8

9.6

8.9

Weight (kg)

Mean

46.7

48.6

54.3

51.0

52.9

50.2

50.4

49.6

SD

7.8

7.9

8.8

3.3

6.6

5.5

8.2

6.4

Race (Asian)

%

100

100

100

100

100

100

100

100

Presence of fever

N

46

22

17

9

36

18

99

49

%

100

100

89

100

100

100

100

100

Temperature (°C)

Mean

37.9

37.9

38.9

38.6

38.9

38.8

38.4

38.4

SD

0.32

0.28

0.92

0.48

0.41

0.48

0.67

0.57

Parasitaemia (μ/L)

Geometric mean

5337.7

5915.1

7547.7

6650.2

6265.1

3279.3

6032.0

4866.3

Hb (g/L)

Mean

98.4

91.1

124.2

113.7

105.7

116.2

105.8

105

SD

25.1

21.0

22.5

19.3

21.9

23.5

25.1

24.5

Populations

Safety/ITT

N

46

22

19

9

36

18

101

49

%

100

100

100

100

100

100

100

100

Per Protocol

N

42

22

19

8

19

11

80

41

 

%

91

100

100

89

53

61

79

84

  1. DP = dihydroartemisinin-piperaquine; A + M = artesunate-mefloquine; SD = standard deviation; fever was considered present if temperature was greater or equal to 37.5 °C; Hb = Haemoglobin.