Guwahati | Goa | Mangalore | TOTAL | ||||||
---|---|---|---|---|---|---|---|---|---|
DP | A+M | DP | A+M | DP | A+M | DP | A+M | ||
(N=46) | (N=22) | (N=19) | (N=9) | (N=36) | (N=18) | (N=101) | (N=49) | ||
Gender (n) | |||||||||
Male : female | 17: 5 | 19: 0 | 8 : 1 | 32 : 4 | 17 : 1 | 78 : 23 | 42 : 7 | ||
Age (years) | |||||||||
Mean | 29.1 | 31.2 | 25.9 | 26.1 | 28.5 | 27.7 | 28.3 | 29.0 | |
SD | 10.9 | 10.2 | 5.5 | 6.8 | 9.6 | 7.8 | 9.6 | 8.9 | |
Weight (kg) | |||||||||
Mean | 46.7 | 48.6 | 54.3 | 51.0 | 52.9 | 50.2 | 50.4 | 49.6 | |
SD | 7.8 | 7.9 | 8.8 | 3.3 | 6.6 | 5.5 | 8.2 | 6.4 | |
Race (Asian) | |||||||||
% | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |
Presence of fever | |||||||||
N | 46 | 22 | 17 | 9 | 36 | 18 | 99 | 49 | |
% | 100 | 100 | 89 | 100 | 100 | 100 | 100 | 100 | |
Temperature (°C) | |||||||||
Mean | 37.9 | 37.9 | 38.9 | 38.6 | 38.9 | 38.8 | 38.4 | 38.4 | |
SD | 0.32 | 0.28 | 0.92 | 0.48 | 0.41 | 0.48 | 0.67 | 0.57 | |
Parasitaemia (μ/L) | |||||||||
Geometric mean | 5337.7 | 5915.1 | 7547.7 | 6650.2 | 6265.1 | 3279.3 | 6032.0 | 4866.3 | |
Hb (g/L) | |||||||||
Mean | 98.4 | 91.1 | 124.2 | 113.7 | 105.7 | 116.2 | 105.8 | 105 | |
SD | 25.1 | 21.0 | 22.5 | 19.3 | 21.9 | 23.5 | 25.1 | 24.5 | |
Populations | |||||||||
Safety/ITT | N | 46 | 22 | 19 | 9 | 36 | 18 | 101 | 49 |
% | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | |
Per Protocol | N | 42 | 22 | 19 | 8 | 19 | 11 | 80 | 41 |
% | 91 | 100 | 100 | 89 | 53 | 61 | 79 | 84 |