Table 1 Characteristics of 204 malaria patients in the copeptin study.

Demographics

Age, years

42 (11-64)

40 (13-69)

39 (8 - 70)

n.s.

Male, female, n (%)

22 (71), 9 (29)

52 (76), 16 (24)

77 (73), 28 (27)

n.s.

Malaria species

falciparum, non-falciparum, n (%)

26 (84), 5 (16)

54 (79), 12 (21)

61 (58), 44 (42)

0.0008

Severe malaria, n (%)

10 (40)

10 (40)

5 (20)

< 0.0001

Parasite load^#, parasites/μL

85900 (400 - 567000) ^{B < 0,001}

11032 (2 - 860000)

4600 (30 - 1380600)

0.0013

Vital signs on admission

Body temperature, °C

39.0 (35.7 - 40.8)

38.9 (35.7 - 41.2)

38.2 (36.0 - 41.2)

0.0315

Pulse rate, beats per minute

100 (58 - 140 ) ^{B < 0,01}

95 (64 - 130)

85 (60 - 130)

0.0109

Systolic blood pressure, mm Hg

120 (80 - 147)

120 (88 - 165)

120 (95 - 196)

n.s.

Laboratory data on admission

C-reactive protein, mg/L

159 (32 - 352) ^{A < 0,01; B < 0,001}

101 (7 - 310) ^{C < 0,05}

78 (7 - 407)

< 0.0001

Haematocrit, L/L

0.35 (0.15 - 0.50) ^{A < 0,01}

0.41 (0.12 - 0.52)

0.39 (0.26 - 0.53)

0.0006

Serum glucose, mmol/L

6.9 (4.1 - 26.0) ^{B < 0,05}

7.0 (4.2 - 10.3) ^{C < 0,001}

6.3 (4.1 - 14.9)

0.0003

Serum creatinine, μmol/L

111 (70 - 1081) ^{B < 0,05}

97 (55 - 135)

93 (46 - 208)

0.0180

Serum urea, mmol/L

6.4 (3.6 - 55.8) ^{B < 0,01}

5.2 (2.2 - 13.5)

4.9 (2.7 - 21.1)

0.0061

Prerenal azotaemia^&, n (%)

2 (6)

2 (3)

2 (2)

n.s.

Copeptin, pmol/L

18.5 (3.3 - 91.5) ^{B < 0,05}

13.2 (1.6 - 71.2)

12.7 (1.6 - 82.9)

0.0268

Duration hospitalisation, days

6 (1 - 13) ^{B < 0,001}

5 (0 - 11) ^{C < 0,001}

3 (0 - 12)

< 0.0001