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Table 3 List of wild type and resistance codon sequences

From: Evaluation of dihydrofolate reductase and dihydropteroate synthetase genotypes that confer resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum in Haiti

Gene

Codon

Wild type codon(s) (amino acid)

Resistance codon(s) (amino acid)

dhfr

51

AAT, AAC (N)

ATT (I)

 

59

TGT (C)

CGT (R)

108

AGC (S)

AAC (N), ACC (T)

164

ATA(I)

TTA (L)

dhps

436

TCT (S)

GCT (A), TTT (F)

 

437

GCT (A)

GGT (G)

540

AAA (K)

GAA (E)