Table 5 Function and details of identification of the significant SNPs associated with high levels of each anti-malarial antibody levels and total IgE levels

AMA1_Pf

rs25882

5 (131411460)

CSF2

T

0.039

NS

rs1881457

5 (131992409)

IL13

T

0.047

S

rs334

11 (5248232)

HBB

A

0.008

NS

rs1799969

19 (10394792)

ICAM1

G

0.043

NS

MSP1_Pf

rs2706348

5 (131933709)

RAD50

G

0.039

rs2227478

12 (68648622)

IL22

A

0.043

S

MSP2

NONE

NANP

rs7537937

1 (89582690)

GBP7

C

0.003

NS

rs1800872

1 (206946407)

IL10

T

0.033

S

rs1800871

1 (206946634)

IL10

A

0.031

S

rs25887

5 (131416061)

CSF2

C

0.013

NS

rs156029

5 (131532634)

P4HA2

A

0.0007

rs272867

5 (131681057)

SLC22A4

G

0.039

rs1881457

5 (131992409)

IL13

T

0.019

S

rs334

11 (5248232)

HBB

A

0.001

NS

AMA1_Pv

rs4986790

9 (120475302)

TLR4

A

0.039

NS

rs1801033

5 (41199959)

C6

A

0.049

NS

MSP1_Pv

rs1801274

1 (161479745)

FCGR2a

T

0.018

NS

rs156029

5 (131532634)

P4HA2

A

0.016

rs848

5 (131996500)

IL13

G

0.030

S

rs2242665

6 (31821494)

CTL4

A

0.015

NS

rs7935564

11 (5718517)

TRIM5

A

0.025

NS

rs10775349

16 (4079823)

ADCY9

G

0.042

S

Total IgE

rs7537937

1 (89582690)

GBP7

C

0.024

NS

rs1518110

1 (206944861)

IL10

C

0.002

S

rs1800872

1 (206946407)

IL10

T

0.001

S

rs1800871

1 (206946634)

IL10

A

0.001

S

rs2243250

5 (132009154)

IL4

C

0.023

S

rs2243270

5 (132014109)

IL4

T

0.039

S

rs3177244

22 (24179132)

DERL3

G

0.043

NS