|
Age, years
|
71
|
65
|
51
|
50
|
49
|
36
|
|
Sex
|
Male
|
Male
|
Male
|
Male
|
Female
|
Female
|
|
Time to death, hours
|
1
|
75
|
16
|
56
|
63
|
84
|
|
Blood pressure, mmHg
|
75/49
|
117/73
|
70/40
|
83/51
|
112/51
|
131/87
|
|
Heart rate per minute
|
127
|
58
|
110
|
89
|
113
|
110
|
|
Oxygen saturation on room air, %
|
75
|
92
|
90
|
60
|
88
|
85
|
|
PaO2:FiO2 ratio
|
NA
|
NA
|
66
|
115
|
91
|
NA
|
|
Axillary temperature, °C
|
39.4
|
36.8
|
37.6
|
37.5
|
36.7
|
37.8
|
|
Haemoglobin, g/dL (females 12.0-16.0, males 13.5-17.5)
|
14.9
|
14.6
|
9.4
|
10.9
|
12.6
|
11.1
|
|
WBC count, x 103 cells/μL (4.5-11)
|
10.8
|
4.8
|
6.8
|
7.81
|
12.1
|
7.8
|
|
Platelet count, x 103 cells/μL (150-450)
|
88
|
58
|
8
|
3
|
32
|
53
|
|
Serum creatinine, μmol/L (63-133)
|
1451
|
NA
|
578
|
330
|
283
|
NA
|
|
Serum urea, mmol/L (1.0–8.3)
|
81.5
|
6.1
|
44
|
38.5
|
25
|
10.8
|
|
Total serum bilirubin, μmol/L (<17)
|
NA
|
NA
|
146
|
74
|
25
|
NA
|
|
Serum aspartate aminotransferase, U/L (<37)
|
42
|
NA
|
53
|
NA
|
39
|
NA
|
|
Serum alanine aminotransferase concentration, U/L (<40)
|
NA
|
NA
|
28
|
49
|
20
|
NA
|
|
Serum albumin, g/L (35-60)
|
NA
|
NA
|
23
|
19
|
28
|
NA
|
|
Serum bicarbonate, mmol/L (18-23)
|
NA
|
NA
|
14
|
16.2
|
14
|
6.5
|
|
Serum lactate mmol/L (0.5-2.2)
|
NA
|
NA
|
6.4
|
6.8
|
NA
|
NA
|
|
Blood cultures
|
negative
|
Not done
|
negative
|
negative
|
Not done
|
Enterobacter cloacae
|
|
Initial microscopic diagnosis
|
P. falciparum”3+” P. malariae “4+”
|
P. malariae “3+”
|
P. malariae “4+”
|
P. vivax “4+”
|
P. malariae “4+”
|
P. malariae “1+”
|
|
PCR result*
|
P. knowlesi
|
P. knowlesi
|
P. knowlesi
|
P. knowlesi
|
P. knowlesi
|
P. knowlesi
|
|
Initial therapy received
|
IV quinine/oral chloroquine, primaquine and doxycycline
|
Oral chloroquine
|
IV artesunate
|
Oral chloroquine and primaquine
|
Oral chloroquine and primaquine
|
Oral sulfadoxine/ pyrimethamine and primaquine
|
