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Table 4 Factors associated with the presence of day-3 parasitaemia after treatment with mefloquine and artesunate 12 mg/kg*

From: Delayed Plasmodium falciparum clearance following artesunate-mefloquine combination therapy in Thailand, 1997–2007

Variable

Level

Day-3 parasitaemia (n)

Univariate

Multivariable

  

yes

no

OR

95% CI

OR

95% CI

Region

East

27

365

2.79

(1.59, 4.90)

4.69

(2.48, 8.88)

 

West

24

905

1.

 

1.

 

Year

1997

0

89

1.12

(0.98, 1.27)

1.29

(1.12, 1.49)

 

1998

0

37

    
 

2002

5

140

    
 

2003

9

180

    
 

2004

10

97

    
 

2005

9

272

    
 

2006

9

307

    
 

2007

9

148

    

Age

≤18

4

229

1.

 

1.

 
 

19-29

31

635

2.79

(0.98, 8.00)

2.43

(0.84, 7.02)

 

≥30

14

348

2.30

(0.75, 7.08)

1.60

(0.50, 5.14)

Parasitaemia

<10000

21

641

1.

 

1.

 

(parasites/μl)

10000-50000

26

522

1.52

(0.85, 2.73)

1.53

(0.84, 2.79)

 

>50000

4

107

1.14

(0.38, 3.39)

1.04

(1.34, 3.19)

  1. Abbreviations: OR, odds ratio; CI, confidence interval.
  2. *Results from both univariate and multivariable logistic regression are presented. Multiple imputation was used for age in the multivariable but not the univariate analyses.
  3. reference level.
  4. Year was coded as a continuous variable so the OR represents the comparison per one year increase in time.