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Table 4 Factors associated with the presence of day-3 parasitaemia after treatment with mefloquine and artesunate 12 mg/kg*

From: Delayed Plasmodium falciparum clearance following artesunate-mefloquine combination therapy in Thailand, 1997–2007

Variable Level Day-3 parasitaemia (n) Univariate Multivariable
   yes no OR 95% CI OR 95% CI
Region East 27 365 2.79 (1.59, 4.90) 4.69 (2.48, 8.88)
  West 24 905 1.   1.  
Year 1997 0 89 1.12 (0.98, 1.27) 1.29 (1.12, 1.49)
  1998 0 37     
  2002 5 140     
  2003 9 180     
  2004 10 97     
  2005 9 272     
  2006 9 307     
  2007 9 148     
Age ≤18 4 229 1.   1.  
  19-29 31 635 2.79 (0.98, 8.00) 2.43 (0.84, 7.02)
  ≥30 14 348 2.30 (0.75, 7.08) 1.60 (0.50, 5.14)
Parasitaemia <10000 21 641 1.   1.  
(parasites/μl) 10000-50000 26 522 1.52 (0.85, 2.73) 1.53 (0.84, 2.79)
  >50000 4 107 1.14 (0.38, 3.39) 1.04 (1.34, 3.19)
  1. Abbreviations: OR, odds ratio; CI, confidence interval.
  2. *Results from both univariate and multivariable logistic regression are presented. Multiple imputation was used for age in the multivariable but not the univariate analyses.
  3. reference level.
  4. Year was coded as a continuous variable so the OR represents the comparison per one year increase in time.