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Table 1 Dosing regimen for each artemisinin-based combination therapy (ACT)

From: Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development

ACT Dosing regimen (WHO)
ARS-MQ ARS 4.0 mg/kg and MQ 8.3 mg/kg at 0, 24, 48 h
ART-LF ART 80.0 mg/kg and LF 480.0 mg/kg at 0, 8, 24, 36, 48, 60 h
DHA-PQ DHA 4.0 mg/kg and PQ 18.0 mg/kg at 0, 24, 48 h
  1. ARS – artesunate, ART – artemether, DHA – dihydroartemisinin, LF – lumefantrine, MQ – mefloquine, PQ – piperaquine.