Table 1 Representative VOCs detected in control and P. falciparum infected cultures using SPME (triple fibre) coupled with GC-MS (Figure 2 )
From: Investigation of volatile organic biomarkers derived from Plasmodium falciparum in vitro
| Â | Â | Relative abundance (%) | |
|---|---|---|---|
Retention time (mins) | Compound | Control cultures | P. falciparum- infected cultures |
1.81 | carbon dioxide | 3539462 (1.39) | 1554307 (0.62) |
2.64 | octane | 646353 (0.25) | 783376 (0.31) |
3.40 | 2,4-dimethyl-1-heptene | 623570 (0.24) | 615473 (0.24) |
4.14 | octamethyl tetrasiloxane* | 724464 (0.28) | 560807 (0.22) |
4.33 | 2,2,4,6,6-pentamethyl heptane | 7031090 (2.76) | 8250249 (3.28) |
4.45 | 4-methyl nonane | 609038 (0.24) | 638770 (0.25) |
5.22 | 2,6-dimethyl nonane | 1740986 (0.68) | 1668518 (0.66 ) |
5.36 | decane | 6616172 (2.59) | 7986280 (3.18) |
5.50 | branched alkane (C11H24) | 1452353 (0.57) | 1453227 (0.58) |
6.07 | 2,6-dimethyl decane | 947057 (0.37) | 1061297 (0.42) |
6.17 | 3,7-dimethyl decane | 716160 (0.28) | 716355 (0.28) |
6.59 | toluene | 1000764 (0.39) | 962309 (0.38) |
6.70 | branched alkene (C11H22) | 1145337 (0.45) | 1218163 (0.48) |
6.92 | unidentified siloxane* | 2167416 (0.85) | 3703832 (1.47) |
7.44 | dodecane | 983881 (0.39) | 1189196 (0.47) |
7.82 | branched alkane (C12H26) | 698815 (0.27) | 1644428 (0.65) |
8.03 | branched alkene (C12H24) | 2883283 (1.13) | 2925879 (1.16) |
8.13 | branched alkene (C12H24) | 2891039 (1.13) | 2873277 (1.14) |
9.59 | alpha-pinene | 516866 (0.20) | 762074 (0.30) |
10.17 | 3-heptanone | 514761 (0.20) | 518528 (0.21) |
10.77 | isopropyl benzene | 404573 (0.16) | 498258 (0.20) |
11.36 | unidentified alkane | 910196 (0.36) | 725047 (0.29) |
11.57 | D-limonene | 451954 (0.18) | 398652 (0.16) |
13.22 | 2-pentyl furan | 979481 (0.38) | 1209153 (0.48) |
15.28 | cyclohexanone | 3714649 (1.46) | 4124560 (1.64) |
19.66 | cyclohexanol | 558229 (0.22) | 682196 (0.27) |
20.49 | 1,3-di-tert-butylbenzene | 10159046 (3.98) | 7908796 (3.15) |
21.28 | 1-octen-3-ol | 796995 (0.31) | 1909838 (0.76) |
22.56 | 2-ethyl-1-hexanol* | 198435706 (77.77) | 191847968 (76.31) |
23.23 | unidentified alkane | 1285623 (0.50) | 1027694 (0.41) |