Figure 3From: Optimizing the HRP-2 in vitro malaria drug susceptibility assay using a reference clone to improve comparisons of Plasmodium falciparum field isolatesIC 50 values of DHA against clinical Plasmodium falciparum field isolates collected from a drug-resistant area in Cambodia (middle and right hand columns), compared to the W2 parasite used as a reference clone (left hand column). Median and interquartile ranges are shown. Median IC50s of DHA were significantly higher for patients with PCT100 >72 hours (9.6 nM) than PCT100 ≤72 hours (6.3 nM, p = 0.0134), and both were significantly higher than the reference W2 clone (3.9 nM, p < 0.0001).Back to article page