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Table 6 Malaria treatment in pregnancy

From: Management of imported malaria in Europe

Uncomplicated falciparum malaria

  

1st trimester (1)

First line

Quinine-clindamycin quinine monotherapy

2nd and 3rd trimester

First line

artemether-lumefantrine

 

Second line

quinine-clindamycin quinine monotherapy mefloquine (2)

Complicated falciparum malaria

  

1st trimester

First line

i.v. quinine (+ follow on treatment)

2nd and 3rd trimester

First line

i.v. artesunate (+ follow on treatment)

 

Second line

i.v. quinine (+ follow on treatment)

P. ovale, P. malariae and P. vivax (3)

  

All trimesters

First line

Oral chloroquine

2nd and 3rd trimester

Second line

Oral ACT

  1. 1. Artemether/lumefantrine is not the first drug of choice due to lack of data on lumefantrine in pregnancy, but should be used if quinine is not available.
  2. 2.http://www.cdc.gov/malaria/new_info/2011/mefloquine_pregnancy.html.
  3. 3. Primaquine should not be used because of the risk of foetal haemolytic anaemia.