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Figure 1 | Malaria Journal

Figure 1

From: Neutral lipids associated with haemozoin mediate efficient and rapid β-haematin formation at physiological pH, temperature and ionic composition

Figure 1

β-haematin formation with NLB gave a high yield at higher lipid/Fe(III)PPIX mol ratios. The high yield stays relatively constant from 2.15 L/H (64.3 μM total lipid) to 0.54 L/H after which the yield suddenly drops to a value of about 10% below 0.13 L/H. Citric buffer (50 mM, pH 4.8), 37°C, 30 min incubation. Constant total Fe(III)PPIX concentration of 30 μM. Error bars represent SEM (L/H = 2.15 and 1.07, n = 6; L/H = 0.54 and 0.27, n = 8; L/H = 0.13 and 0.067, n = 4; L/H = 0.033, n = 2).

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