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Table 2 Frequency of different genotypes in healthy (control) subjects ( f c ) and in malaria (diseased) patients ( f d ) [[56]]

From: Resistance to malaria in humans: the impact of strong, recent selection

  

Genotype

 

AA

AC

AS

CC

SC

SS

f c

0.664

0.217

0.095

0.016

---

--

f d

0.804

0.164

0.028

0.001

  

OR

2.070

0.708

0.268

0.072

---

---

Relative fitness

0.95

1.03

1.08

1.10

---

---

 

0.86

0.94

0.98

1

0.50

0.11

  1. The OR values for the genotypes and the estimated relative fitnesses are given (m = 0.1). In the bottom row, these values are standardized by the fitness of genotype CC, the genotype with the highest fitness [53].
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Malaria Journal

ISSN: 1475-2875

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