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Table 2 Comparison of the major alleles encountered in the Malawi consecutive patient data set in one season (n = 112) compared with the same allele for the set of global parasites previously published (n = 114).

From: Human cerebral malaria and Plasmodium falciparum genotypes in Malawi

Assay

Malawi

Original

Difference

z-score

p-value

1

0.6446

0.8690

0.2244

-7.1029

<0.05

2

0.9099

0.8475

0.0625

1.8546

NS

3

0.6591

0.6885

0.0294

-0.6786

NS

4

0.8182

0.6446

0.1736

3.8716

<0.05

5

0.7653

0.7698

0.0045

-0.1150

NS

6

0.6269

0.6154

0.0115

0.2520

NS

7

0.6270

0.4640

0.1630

3.4894

<0.05

8

0.8130

0.8034

0.0096

0.2576

NS

9

0.7481

0.5873

0.1608

3.4871

<0.05

10

0.6391

0.6111

0.0280

0.6130

NS

11

0.6529

0.3220

0.3309

7.5603

<0.05

12

0.5620

0.4274

0.1346

2.9058

<0.05

13

0.6504

0.5289

0.1215

2.5985

<0.05

14

0.7241

0.6239

0.1002

2.2087

<0.05

15

0.5489

0.5124

0.0365

0.7791

NS

16

0.7652

0.4872

0.2780

5.9392

<0.05

17

0.5556

0.6032

0.0476

-1.0392

NS

18

0.6330

0.5124

0.1206

2.5768

<0.05

19

0.5909

0.6250

0.0341

-0.7519

NS

20

0.6692

0.6230

0.0462

1.0183

NS

21

0.5231

0.4318

0.0913

1.9671

<0.05

22

0.5766

0.3953

0.1813

3.9591

<0.05

23

0.6866

0.6518

0.0348

0.7795

NS

24

0.9231

0.5897

0.3333

7.2356

<0.05

  1. Thirteen assays are significantly different from the population observed in the original study with the differences ranging from 9.1 to 41.0%. Assay 24 is non-informative in the Malawi population