From: Evaluation of the malaria rapid diagnostic test SDFK90: detection of both PfHRP2 and Pf-pLDH
Microscopy corrected by PCR | Number | % Sensitivity PfHRP2 line (95% CI) | % Sensitivity Pf-pLDH line, (95% CI) | McNemar (p-value) |
---|---|---|---|---|
All P. falciparum samples | 336 | 97.3 (95.0-98.8) | 86.9 (82.8-90.3) | 0.0001 |
Pure gametocytaemia | 18 | 77.8 (52.4-93.6) | 61.1 (35.8-82.7) | 0.4497 |
Asexual parasite density 1-100/μl | 36 | 97.2 (85.5-99.9) | 30.6 (16.4-48.1) | 0.0001 |
Asexual parasite density 101-200/μl | 19 | 100 (82.4-100) | 73.7 (48.8-90.9) | 0.0736 |
Asexual parasite density 201-1,000/μl | 44 | 95.5 (84.5-99.4) | 88.6 (75.4-96.2) | 0.3711 |
Asexual parasite density >1,000/μl | 219 | 99.1 (96.7-99.9) | 99.1 (96.7-99.9) | 0.4795 |
Asexual parasite density >100/μl | 282 | 98.6 (96.4-99.6) | 95.7 (92.7-97.8) | 0.0433 |
Excluding pure gametocytaemia | 318 | 98.4 (96.4-99.5) | 99.1 (97.3-99.8) | 0.4658 |