Table 1 Percentages of individuals within the Asymptomatic (Asy) and Symptomatic (Sym) malaria groups responding (total IgG) to EBL and PfRh ligands
Ligand | PfRh1 | PfRh2a | PfRh2b | PfRh4 | PfRh5 | EBA- 175 | EBA- 140 | EBA-181 | MSP-119 |
|---|---|---|---|---|---|---|---|---|---|
Asy | 100% | 75% | 75% | 71% | 25% | 100% | 25% | 88% | 100% |
Seropositive | (8/8) | (6/8) | (6/8) | (5/7) | (2/8) | (8/8) | (2/8) | (7/8) | (8/8) |
Sym | 86.5% | 75.7% | 21.6% | 47% | 8.1% | 32. 4% | 5.4% | 21.6% | 54% |
Seropositive | (32/37) | (28/37) | (8/37) | (17/36) | (3/37) | (12/37) | (2/37) | (8/37) | (20/37) |
Cut-off value | 0.13 | 0.12 | 0.1 | 0.1 | 0.16 | 0.16 | 0.41 | 0.12 | 0.16 |
p (Fisher Test) | ns | ns | 0.007 | ns | ns | 0.0006 | ns | 0.0009 | 0.0171 |