Table 5 Risk of severe disease among adult patients with Plasmodium knowlesi malaria – multivariate modeling
From: Laboratory markers of disease severity in Plasmodium knowlesi infection: a case control study
Model | Variables | Adjusted OR (95% CI) | p value† | |
|---|---|---|---|---|
Model 1 | Platelet count | ≥60 | 1 | |
(x 103 platelets/μl) | 36-59 | 10.37 (1.79 – 59.98) | 0.002 | |
≤35 | 12.28 (2.04 – 73.86) | |||
Parasite count | <100000 | 1 | 0.0006 | |
(parasites/μl) | ≥100000 | 10.74 (2.63 – 43.94) | ||
Model 2 | Platelet count | ≥60 | 1 | |
(x 103 platelets/μl) | 36-59 | 8.69 (1.59 – 47.48) | 0.018 | |
≤35 | 5.59 (0.99 – 31.34) | |||
Parasite count | <2 | 1 | 0.003 | |
(% IRBC) | ≥2 | 5.97 (1.79 – 19.88) | ||
Model 3 | Platelet count | ≥60 | 1 | |
(x 103 platelets/μl) | 36-59 | 4.75 (0.74 – 30.36) | 0.04 | |
≤35 | 9.29 (1.37 – 62.86) | |||
PCN count | 0 | 1 | ||
(PCN/μl) | 1 – 139 | 0.54 (0.04 – 6.63) | <0.0001 | |
140 – 415 | 4.8 (0.66 – 34.83) | |||
≥416 | 30.25 (4.74 – 193.22) |