Skip to main content

Table 8 Risk of severe disease in patients with Plasmodium knowlesi malaria using the recommended cut-offs – multivariate modeling

From: Laboratory markers of disease severity in Plasmodium knowlesi infection: a case control study

Variable

Uncomplicated malaria n (%)

Severe malaria n (%)

Adjusted odds ratio (95c% CI)

p-value†

Parasite count (parasites/μl)

<35000

79 (71.8)

6 (35.3)

1

0.0001

≥35000

14 (28.2)

11 (64.7)

9.93 (2.91 – 33.87)

Parasite count (% IRBC)

<1

73 (78.5)

6 (35.3)

1

0.003

≥1

20 (21.5)

11 (64.7)

5.72 (1.78 – 18.37)

Platelet count (x 103 platelets/μl)

>45

67 (72)

5 (29.4)

1

0.004

 

≤45

26 (28)

12 (70.6)

5.27 (1.59 – 17.41)*

 
  1. 95% CI 95% confidence interval.
  2. % IRBC % infected red blood cells.
  3. †All p-values were obtained from likelihood ratio test.
  4. *The odds ratio was obtained by including the platelet count into one model with parasite count (% IRBC) measured on thin blood films.
Back to article page

Malaria Journal

ISSN: 1475-2875

Contact us