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Table 4 Sequence analysis of SNPs in full-length pfatpase6 among 40 P. falciparum clinical isolates unexposed (n = 20) and exposed (n = 20) to ACT

From: Molecular assessment of atpase6 mutations associated with artemisinin resistance among unexposed and exposed Plasmodium falciparum clinical isolates to artemisinin-based combination therapy

A: Nonsynonymous      
Position ≤2007 >2007
nt aa   Codon
n=20 n=20
266 89 T AcA 0.25 0
   I AtA 0.75 1
689 230 I AtC 0.95 1
   T AcC 0.05 0
1063 355 I aTA 1 0.7
   L tTA 0 0.3
1291 431 E gAA 0.45 0.40
   K aAA 0.55 0.60
1707 569 K AAa 0.25 0
   N AAt 0.75 1
1888 630 T aCT 0 0
   H gCT 0.95 1
   S tCT 0.05 0
2049 683 K AAa 0 0.05
   N AAt 1 0.95
2306 769 S AgT 1 0.87
   N AaT 0 0.13
2610 870 F TTt 1 0.95
   L TTa 0 0.05
B: Syonymous      
981 327 A GCa 0.05 0
   A GCt 0.95 1
1449 483 N AAc 0.2 0
   N AAt 0.8 1
2694 898 I Ata 0.8 0.95
   I ATt 0.2 0.05
2703 901 V GTa 0.95 1
   V GTt 0.05 0
3090 1030 K AAa 0.05 0.05
   K AAg 0.95 0.95
3093 1031 C TGc 0.95 1
   C TGt 0.05 0
3309 1103 Y Tat 0.95 1
   Y TAc 0.05 0
  1. nt: nucleotide.
  2. aa: amino acid.