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Figure 2 | Malaria Journal

Figure 2

From: Ivermectin inhibits the sporogony of Plasmodium falciparum in Anopheles gambiae

Figure 2

Proportion of Anopheles gambiae that contained sporozoites when ivermectin (LC 25 ) was ingested DPIs 3, 6, 9. When ivermectin (LC25) was fed at DPI 3 post parasites it did not reduce the proportion of An. gambiae that contained sporozoites at DDPI 12 (χ2 = 4.3718, P = 0.0556, n = 112) or at DDPI 14 (χ2 = 0.0113, P = 1, n = 145). However, when ivermectin (LC25) was fed at DPIs 6 and 9 post parasites it reduced the proportion of An. gambiae that contained sporozoites on DPI 6 at DDPI 12 (χ2 = 12.4919, P = 0.0006, n = 95) and at DDPI 14 (χ2 = 8.5103, P = 0.0044, n = 135) and on DPI 9 at DDPI 12 (χ2 = 16.2056, P < 0.0001, n = 132) and at DDPI 14 (χ2 = 14.7998, P < 0.0001, n = 161). * significantly different P < 0.05, DPI = days post infection, DDPI = dissected at day post infection.

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