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Table 1 Hematological parameters

From: Foetal haemoglobin and the dynamics of paediatric malaria

Parameter

Symbol

Value

Maximum adult reticulocyte production rate per kilogram of tissue

Pamx,

1.21 × 108 (kg hr) -1

Maximum foetal reticulocyte production rate per kilogram of tissue

Pfmx

1.7 × 108 (kg hr) -1

Minimum foetal reticulocyte production rate per kilogram of tissue

Pfmn

2.48 × 106 (kg hr) -1

Time offset for production of adult erythrocytes

t OSa

50 days

Time constant for production of adult erythrocytes

Ï„Ca

75, 150, and 300 days

Time constant for decay of production of foetal reticulocytes

Ï„Cf

50, 100, and 200 days

Volume of adult red blood cell

V a

8.0 × 10-8 μm3

Volume of foetal red blood cell

V f

1.25 × 10-7 μm3

  1. Baseline parameters for adult (HbA) and foetal (HbF) RBCs [44].