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Figure 2 | Malaria Journal

Figure 2

From: A population pharmacokinetic model of piperaquine in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum malaria in Sudan

Figure 2

Monte-Carlo Mapped Power (MCMP) curve for identifying pregnancy as a covariate. Triangles represents the power curve for indentifying pregnancy as covariate on apparent elimination clearance and circles is the power curve for identifying pregnancy as a covariate on the relative bioavailability. The dotted black line represents 80% power. The inserted numbers are the total number of subjects needed to identify pregnancy as a covariate given the used model and study sampling procedure.

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