Artesunate Mefloquine (n = 157) | Artemether Lumefantrine (n = 153) | p value | |
---|---|---|---|
Age (mean ± SD, years) | 25 ± 11 | 23.2 ± 10,5 | 0.15 |
Weight (mean ± SD, Kg) | 62.1 ± 11.8 | 58.2 ± 11.5 | 0.08 |
Sex ratio (male/female) | 1.2 | 0.6 | 0.03 |
Temperature (mean ± SD) | 37.8 ± 1.2 | 37.7 ± 1.1 | 0.41 |
Median Parasitemia (trophozoites/μL) | 17411 | 17688 | 0.88 |
Mean haemoglobin (g/dl) | 12.2 ± 1.7 | 11.7 ± 1.7 | 0.99 |
Anaemia (Hb < 11 g/dl,%) | 36.3 | 40.5 | 0.44 |
ASAT (UI/L, mean ± SD) | 31.2 ± 18.7 | 33.1 ± 16.8 | 0.38 |
Patients with normal level of ASAT (ASAT < 40 UI/L) (%) | 128 (81.5%) | 123 (80.4%) | 0.79 |
ALAT (UI/L, mean ± SD) | 28.2 ± 20.3 | 26.3 ± 24.1 | 0.47 |
Patients with normal level of ALAT (ALAT < 40 UI/L) (%) | 119 (82.1%) | 138 (90.2%) | 0.04 |
Creatinine (mean ± SD) | 7.6 ± 5.4 | 8.2 ± 3.5 | 0.24 |
Patients with normal level of creatinine (<13 mg/L) (%) | 148 (94.3%) | 143 (93.5%) | 0.76 |
Median Bilirubunemia (mg/L) | 1.91 | 1.71 | 0.51 |
Patients with normal level of Biliribunemia (<10 mg/L) (%) | 48 (30.6%) | 55 (35.9%) | 0.31 |