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Figure 2 | Malaria Journal

Figure 2

From: Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common

Figure 2

Dose–response relationships for primaquine in reducing the infectivity of P. falciparum infected subjects to anopheline mosquitoes. Vertical axis shows the proportion of fed anopheline mosquitoes which were infected. Pooled data from all studies conducted[15, 28]. Left: Oocyst formation (proportion of patients who were still infectious to mosquitoes) from blood sampled 24 hours after primaquine dose, Right : Oocyst formation from blood sampled 48 hours after primaquine dose. Primaquine given with an artemisinin derivative is shown in green, and with a non-artemisinin derivative or no anti-malarial is shown in red. In these studies 29 patients received no primaquine. The size of the circle is proportional to the number of subjects in each group (shown within).

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Malaria Journal

ISSN: 1475-2875

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