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Table 2 Biological parameters evolution between day 0 and day 7

From: Multicentre study evaluating the non-inferiority of the new paediatric formulation of artesunate/amodiaquine versus artemether/lumefantrine for the management of uncomplicated Plasmodium falciparum malaria in children in Cameroon, Ivory Coast and Senegal

Parameters

AS-AQ

 

AL

 
 

D0

D7

p

D0

D7

p

Mean Hb level (g/dl)

9,5 ± 2

9.3 ± 1.5

0.75

10 ± 2

9.6 ±16

0.63

Anemia

71,9

87,1

<10-3

66,4

78,9

0,002

(Hb < 11g/dl) (%)

Patient with abnormal

8.4

4.4

0,05

7.3

6

0.25

ALAT (<40 UI/L) (%)

Patient with abnormal

30.1

10

<10-3

27.6

12.9

<10-3

ASAT (<40 UI/L) (%)

Mean bilirubine level

11.2 ±8.5

7.3 ±3.6

0.58

11.8 ± 11.4

7.4 ±3.4

0.55

Mean Creatinin level

5.8 ±2.4

5.9 ±2.5

0.99

6 ±2.2

5.8 ± 2.3

0.85