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Table 3 Treatment outcome of AS+AQ versus AL at D28

From: Multicentre study evaluating the non-inferiority of the new paediatric formulation of artesunate/amodiaquine versus artemether/lumefantrine for the management of uncomplicated Plasmodium falciparum malaria in children in Cameroon, Ivory Coast and Senegal

  Artesunate/Amodiaquine Artemether/Lumefantrine p value
Overall treatment outcome
ITT analysis    
Early treatment failure 00 00 --
Crude parasitological failure at day 28 05/249 (2%) 10/232 (4.3%) 0.14
PCR adjusted failure rate at day 28 04/249 (1.6%) 09/232 (3.8%) 0.12
PCR adjusted ACPR at day 28 242/249 (97.6%) 218/232 (94.8%) 0.11
Difference, % [95%CI] 2.7 [-0.6 - 6.2%]
PP analysis
Early treatment failure 00 00 --
Crude parasitological failure at day 28 05/246 (2%) 10/227 (4.4%) 0.14
PCR adjusted failure rate at day 28 04/246 (1.6%) 09/227 (3.9%) 0.12
PCR adjusted ACPR at day 28 242/246 (98.7%) 218/227 (96.9%) 0.16
Difference, % [95%CI] 1.8 [-0.76 - 4.4]