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Table 1 Descriptive statistics of study cohort

From: Increasing incidence of malaria in children despite insecticide-treated bed nets and prompt anti-malarial therapy in Tororo, Uganda

Characteristic

Findings

Number of children enrolled

100

Median age at enrolment in months (range)

5.52 (1.50-9.93)

Female, n (%)

40 (40%)

Rural residence, n (%)

76 (76%)

Number of children who reached four years of age, n (%)

79 (79%)

Median years of follow-up (IQR)

3.46 (3.24-3.66)

Proportion who reported sleeping under an LLIN* (%)

3,934/4,008 (98%)

Antimalarial group children were randomized to, n (%)

 

 DP

51 (51%)

 AL

42 (42%)

 Never randomized

7 (7%)

Total incident episodes of malaria**

1,633

 Uncomplicated malaria treated with DP

847

 Uncomplicated malaria treated with AL

778

 Uncomplicated malaria treated with quinine for age <4 months

2

 Quinine for complicated malaria

6

Treatments for malaria within 14 days of prior episode

12

 Quinine for early treatment failure following AL

5

 Quinine for recurrent malaria on day 14 following AL

2

 Quinine/clindamycin for early treatment failure following quinine

3

 Quinine/clindamycin for recurrent malaria days 4–14 following quinine

2

Median malaria incidence through four years of age per person years (IQR)

5.44 (3.18-7.00)

Total episodes of asymptomatic parasitaemia

186

Monthly prevalence of asymptomatic parasitaemia

5.0%

  1. Note: IQR, interquartile range; LLIN, long-lasting insecticide treated bed net; DP, dihydroartemisinin-piperaquine; AL, artemether-lumefantrine.
  2. * Assessed at the time of monthly routine visits to the clinic.
  3. ** All treatments for malaria not proceed by another treatment in the prior 14 days.