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Figure 3 | Malaria Journal

Figure 3

From: Bacterium-like particles as multi-epitope delivery platform for Plasmodium berghei circumsporozoite protein induce complete protection against malaria in mice

Figure 3

Immune responses and protection BLP-PbCSP1. BLP-PbCSP1 induced (A) IgG antibodies against B-cell epitopes ([PPPPNPND]2x-[NANDPAPP]2x) and (B) IFN-γ response against CTL (SYIPSAEKI) and Th (KQIRDSITEEWS) P. berghei CSP epitopes. (C + D) Post-challenge parasitaemia percentages and pre-patency upon detailed view of the first seven days of infection. Median are presented on all plots with individual values. Error bars represent SEM. * = p < 0.05, ** = p < 0.01, *** = p < 0.001.

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Malaria Journal

ISSN: 1475-2875

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